PharmOptima LLC 4717 Campus Drive Kalamazoo, Michigan 49008 Phone 269-372-8704 FAX 269-544-1088

www.pharmoptima.com

CORPORATE MISSION

To provide professional drug discovery and research services to optimize our clients’ chances of success.

KEY CONTACTS

A. Christian Schauer, C.P.A.
Chief Executive Officer
cschauer@pharmoptima.com

Stephen Buxser, Ph.D.
Vice President
Chief Scientific Officer
stephen.buxser@pharmoptima.com

Allen Buhl, Ph.D.
Vice President
Contract Research
aebuhl@pharmoptima.com

J. James Vrbanac, Ph.D.
Director, Pharmacokinetics Dynamics & Metabolism (PDM)
jjvrbanac@pharmoptima.com

COMPANY HISTORY

PharmOptima is a contract research organization (CRO) founded in 2003 by a group of senior discovery and research scientists from Pharmacia. With over 300 years combined experience, the team brought together expertise in most phases of drug discovery and research, including discovery assay development, high throughput screening, lead optimization, ADME and in vivo proof-of-concept testing.

CORPORATE HIGHLIGHTS

Currently PharmOptima provides services in three areas:

• Biochemical Mechanism of Action
  • Biochemical Mechanism of Action determinations and early identification of a compound’s mechanism of action
• Assay Development and High Throughput Screening
  • Assay design and development to optimize high throughput screening
  • HTS strategies and analysis
  • Integrated prospective research strategies to optimize chances of success
  • Turning hits into leads through designing and implementing secondary assays
• ADME and in vivo Proof of Concept Testing
  • Proof of concept testing for compound availability, efficacy, tolerance and ADME

PharmOptima scientists have a successful track record in cardiovascular, cancer, dermatology and infectious diseases with over 300 cumulative years of experience, 400 publications, and inventors on 100 patents.

Page last updated January 11, 2005.
www.picra.org